PENGARUH LUMATAN DAUN PLETEKAN (Ruellia Tuberosa L) TERHADAP LAMA PENUTUPAN LUKA PADA TIKUS PUTIH (Rattus Novergicus)
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Abstract
Wounds is defined as disruption of the function and integrity of body tissues. Wound healing is
a complex process of tissue repair and remodelling in response to injury. Pletekan (ruellia
tuberosa l) contains flavonoids, glycosides, phenols, saponins and nutritive value that suppose to
accelerate wound healing. The purpose of this study was to identify the effect of pletekan leaves
(ruellia tuberosa) to wound closure time in rats (rattus novergicus). This research was an
experimental study with post- test design using the simple random sampling technique. The
samples were 40 male rats with a clean incision wound along 3 cm which were divided into two
groups, control group and treatment group. The measured data were the average of wound
closure time. Data were analyzed using the mann- whitney test with 95 % confidence level
showed a significant difference between the control group (8,45) and the treatment group (3,75)
with p-value 0,000 (p<0,005). There was significant effect of ruellia tuberosa l to wound closure
time in rattus novergicus.
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